Pediatric Radiation Oncology

We provide advanced radiation therapy, customized to support each child's long-term health.
Pediatric Radiation Oncology

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Why choose UCSF Benioff Children's Hospitals for radiation therapy?

Children and young adults have unique needs during cancer treatment. Because their bodies are still growing and developing, they're more sensitive to radiation.

At UCSF Benioff Children's Hospitals, our team delivers treatment with exceptional precision while reducing radiation exposure to the rest of the body. We personalize each child's care to minimize side effects and protect their long-term health and quality of life.

Our approach to radiation therapy for childhood cancers

Our pediatric radiation oncologists use radiation therapy to treat many childhood cancers, including:

  • Brain tumors

  • Neuroblastomas

  • Wilms tumors

  • Bone and soft tissue sarcomas

Depending on your child's diagnosis, radiation therapy may be their main treatment, or it might be used alongside surgery or chemotherapy. Radiation therapy can shrink tumors so they're easier to remove during surgery. For children with advanced cancer, it can help relieve pain and improve comfort.

Precise treatment planning

We carefully plan radiation therapy to make treatment as safe and effective as possible. Our team uses advanced imaging to map the exact shape and location of the tumor for the most precise treatment.

We also do practice (simulation) treatment sessions to help children understand what to expect and how they'll be positioned. For younger children who may need sedation, we work closely with pediatric anesthesiologists to keep them calm and comfortable.

Types of radiation therapy we offer

Our team offers the latest types of external beam radiation therapy (EBRT) and several other highly specialized treatments.

Our EBRT capabilities include:

  • Intensity-modulated radiation therapy (IMRT). This treatment uses multiple beams of radiation to deliver a highly focused dose while sparing healthy tissue.

  • Volumetric modulated arc therapy (VMAT). This technique delivers radiation rapidly from multiple angles by rotating in an arc around the patient.

  • Total body irradiation (TBI). We offer TBI for children with leukemia or lymphoma who need stem cell transplants.

  • Electron beam therapy. We may use this to treat tumors near the surface of the body, such as skin cancer or certain soft tissue sarcomas.

  • Stereotactic radiosurgery using Gamma Knife. This innovative technique delivers a highly precise, intense dose of radiation to small brain tumors that have returned after treatment. We may also use Gamma Knife to treat vascular malformations (tangles of blood vessels).

Our radiation therapists also offer techniques not widely available in the Bay Area, including:

  • Brachytherapy. A surgeon places radioactive seeds inside or near a tumor to deliver high doses of radiation while avoiding healthy tissue. This can be beneficial for children who previously received EBRT because it limits additional radiation exposure.

  • Hyperthermia therapy. After EBRT or chemotherapy, we may apply heat to a tumor, so cancer cells are less able to repair themselves after treatment.

  • Intraoperative radiation therapy (IORT). During surgery, we deliver targeted radiation to tumors that are difficult to remove. This allows radiation treatment to be completed in a single session, right away, instead of in multiple sessions after surgery.

If your child needs proton beam therapy, we help arrange a referral and coordinate their care at an appropriate facility.

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    Awards & achievements

    Recognized nationally for excellence, we pair world-class medical expertise with compassionate care to deliver the best possible outcomes for patients.
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    • U.S. News & World Report Best Children's Hospitals 2026-2027, cancer

      Best in Northern California and top 10 in the nation for cancer care

    • Designated an early phase clinical trials core site by the Children's Oncology Group

    • U.S. News & World Report Best Children's Hospitals 2026-2027, ranked in 11 specialties

      Ranked among the nation's best in 11 specialties

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    Related conditions & treatments

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    Trials & research

    • This phase II trial studies how well lower dose radiotherapy after chemotherapy (Carboplatin & Etoposide) works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class of medications known as platinum-containing compounds...

    Research initiatives